New Web content editors and creators are invited to bring sign-on credentials (username and password) and their converted site URL (http://unlcms.unl.edu/~/ and spend a couple of hours with Mark Hiatt, going over the basics of creating, editing and deleting pages and components of your Web site in the new UNLcms. Learn to edit pages, footers, navigation and headings and learn to assign roles and permissions to users. A short break is provided, along with plenty of time for questions and answers.

"Oxidative Stress Induced by Alcohol Consumption Alters the Functions of Liver Sinusoidal Endothelial Cells and the Immune System," will be presented by Geoffrey M. Thiele, Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center. Oxidative stress caused by alcohol consumption causes the production of many metabolites (aldehydes) of ethanol that can bind to and modify proteins. Studies in our laboratory have evaluated the role of these aldehyde modified proteins in the development and/or progression of alcoholic liver disease (ALD). More specifically, the original studies investigated the biological responses of liver sinusoidal endothelial cells (LSECs) to these modified proteins in the presence and absence of ethanol with respect to; receptor mediated endocytosis, cytokine secretion, and adhesion molecule expression. Since alcohol inhibited the clearance of these aldehyde modified proteins and initiated a pro-inflammatory environment by LSECs, studies were then expanded to determine whether the immune system is initiated and contributes to the pathogenesis of ALD. These studies have resulted in many publications and presentations, as well as, funding from both the NIH and VA.

“Dividing the Waters: Global Security in a Water-Stressed World”

The Student Brass Chamber Ensembles will perform in concert on Tuesday, Nov 1 at 7:30 pm in Westbrook Recital Hall, Room 119. This event is FREE and open to the public.