Dr. John J. Mieyal, Professor and Vice-Chairman of Pharmacology, Case Western Reserve University will present the seminar "Reversible Protein S-Glutathionylation in Redox Regulation -- Implications for Thiol Homeostasis and Signaling in Health and Disease" on Tuesday, October 30, 2012 at 4PM in N172 Beadle.
Dr. John Mieyal received his B.S. degree in Chemistry from John Carroll University. He earned his Ph.D. degree in Biochemistry from Case Western Reserve University. Dr. Mieyal did postdoctoral re-search studies at Brandeis University, and he began his independent academic career at Northwestern University with a joint appointment in the Departments of Pharmacology and Biochemistry.
Dr. Mieyal is Professor and Vice-Chairman of the Department of Pharmacology where he conducts his research program and oversees the educational mission of the Department. He holds joint appointments in the departments of Chemistry and Environmental Health Sciences, and in the Comprehensive Cancer Center. He also holds a Research Chemist appointment at the Louis B. Stokes Veterans Affairs Medical Research Center. Current research emphasis in Dr. Mieyal’s laboratory is focused on mechanisms of alterations in redox regulation in Parkinson’s disease and cardiovascular diseases, both prevalent among the elderly. The research team has appreciated funding from the National Institutes of Health and the Department of Veterans Affairs.
Dr. Mieyal is recognized internationally for advancing knowledge of redox regulation and signal transduction in health and disease, especially involving the glutaredoxin and thioredoxin enzyme systems. Professor Mieyal has been a featured speaker at many international symposia on Redox Regulation and Thiol Homeostasis in recent years, including those sponsored by the American Society of Biochemistry and Molecular Biology, the International Redox Network, and the International Gordon Conferences. He has served on scientific review boards for the American Heart Association and the Department of Veterans Affairs, and he is recently was guest editor for a special Forum Issue of the premier journal Antioxidants and Redox Regulation. Besides recognition for his research, Dr. Mieyal has won several University awards for his medical and graduate school teaching and mentorship, most recently the first annual Inamori Award for Excellence in Mentoring, and he has served on the Pharmacology Committee of the National Board of Medical Examiners.