"Choline Oxidase and Related Systems" will be presented by Dr. Giovanni Gadda, Associate Professor, Chemistry Department, Georgia State University. My scientific interest is in the general area of the mechanistic enzymology of redox enzymes, with a specific interest in flavin-dependent enzymes. The long-term objectives are to understand how enzymes can influence the energetics of reaction intermediates and transition states. These aspects are being studied by steady state kinetics and rapid reaction techniques using pH, viscosity and kinetic isotope effects, as well as mutagenesis and X-ray crystallography. Several enzymes from diverse cellular sources are currently investigated, including choline oxidase, nitronate monooxygenase, glycolate oxidase, D-arginine dehydrogenase, and others. Significant advances on the understanding of the enzyme-cvatalyzed, flavin-dependent mechanisms for alcohol and amine oxidation have been obtained. Results from my laboratory aided in the reclassification of 2-nitropropane dioxygenase as nitronate monooxygenase by the IUBMB in 2010.