Dr. Grant Hatch will present the seminar, "Linking Cardiolipin to T-Cell Function and Mitochondrial Beta-oxidation" on Tues., Feb. 5, 2013 in N172 Beadle Center.

Cardiolipin is a major mitochondrial membrane phospholipid involved in energy production. Alteration in the content and fatty acid composition of cardiolipin result in defects in mitochondrial oxidative phosphorylation.

Dr. Hatch’s research program explores the role of more subtle defects in cardiolipin that could explain susceptibility to diseases that have their biological basis in mitochondrial dysfunction. He is testing test whether correction of these subtle defects in cardiolipin may lead to treatment and prevention of genetic and chronic disease.