All events are in Central time unless specified.

John West – CBC/RBC Seminar

Date: Time: 4:00 pm–5:00 pm
Beadle Center Room: N172
1901 Vine Street
Lincoln NE 68588
Contact: Paula Adams, 402-472-3173,
Dr. John T. West, research associate professor, Nebraska Center for Virology, University of Nebraska–Lincoln will present “Translating Basic Science Discovery into Interventions Against HIV-1 and HIV-associated Malignancies.”

Antiretroviral therapy (ART) has had a profound effect on the global human immunodeficiency virus type 1 (HIV-1) epidemic, by reducing viral load, promoting reconstitution of immune function, and extending and improving quality of life. Despite these advances mediated through an armamentarium of antivirals, HIV-1 associated malignancies, such as Kaposi’s sarcoma (KS), continue to occur at high levels, especially in sub-Saharan Africa, despite suppression of HIV-1 replication. We will discuss our current understanding and remaining questions about KS, and its etiologic agent the KS-associated herpesvirus (KSHV)/human herpesvirus-8 (HHV-8). The focus will be on the virus-host interaction, the role of HIV-1, the immune response to KSHV and to KS, and how we might move from understanding aspect of KSHV basic biology and tumorigenesis to intervention against this devastating disease.

Additional Public Info:

Download this event to my calendar