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Dr. Huilin Li – CBC/RBC Seminar

Molecular mechanism of energy conservation and evolution in a thermophilic archaea

4:00 pm–5:00 pm
Beadle Center Room: N172
Directions: Beadle Center is located at 1901 Vine St. Lincoln, NE, on the University of Nebraska–Lincoln campus.
Additional Info: BEAD
Diana Bonham, (402) 472-2932,
Over the past four billion years, life on earth has evolved from hydrogen breathing, to sulfur breathing, and eventually to oxygen breathing. Underlying these dramatic changes is the evolution of the energy-conserving respiratory complexes, from membrane-bound hydrogenase (MBH), to membrane-bound sulfane reductase (MBS), and finally to the modern-day Complex I. Dr. Li will describe their structural analyses of MBH and MBS isolated from the membranes of extreme thermophile Pyrococcus furiosus, and compare these structures with the modern-day Complex I, highlighting a key structural feature nature has evolved to enable energy transduction from the redox potential to chemical gradient.

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This event originated in Biochemistry.