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SVMBS Research Seminar Series – Matthew Hille

Leveraging genomics of Moraxella bovoculi using MALDI-TOF technology: implications for prevention and diagnostics of bovine pinkeye

Date: Time: 4:00 pm
SVMBS Zoom Webinar
Contact: Marcia Oetjen, moetjen1@unl.edu
Moraxella bovoculi is the most frequently isolated bacteria from the eyes of cattle with Infectious Bovine Keratoconjunctivitis (IBK), also known as bovine pinkeye. Two distinct genotypes of Moraxella bovoculi, genotype 1 and genotype 2, were characterized after whole genome sequencing showed a large degree of single nucleotide polymorphism (SNP) diversity within the species. To date, only genotype 1 strains have been isolated from the eyes of cattle with clinical signs of IBK. Approximately 80% of genotype 1 Moraxella bovoculi isolates have been shown to possess complete repeats-in-toxin (RTX) operons which encode for a secreted exotoxin that induces hemolysis of bovine erythrocytes.

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