Nebraska Food for Health Center member Dr. Jonathan B. Clayton, Department of Biology at UNO, Food Science & Technology at UNL, will present, “Modeling host-microbiome relationships in the primate gut”, via Zoom as part of the Food for Health Seminar Series.

Talk Abstract: The primate gastrointestinal tract is home to trillions of bacteria that play major roles in digestion and metabolism. Among other important aspects of host health and behavior, this anatomical site is also critical for immune system development, immune system function and pathogen resistance. Furthermore, diverse communities of microbes are also present in many body sites other than the gut. To gain greater insights into the causal mechanisms for microbiome-modulated metabolic diseases, the Clayton Lab is studying host-microbiome interactions in humans and nonhuman primates. We are also exploring neurological/behavioral diseases such as depression to better understand the impact of the microbiome on the gut-brain axis. We do all of this using in vitro as well as in vivo experiments together with powerful analysis approaches including next-generation sequencing, anaerobic and aerobic culture, germ-free mice models, and nonhuman primate models. The nonhuman primate model regularly used in the lab is the common marmoset (Callithrix jacchus). During this presentation, I will provide an overview of the current projects in the lab, including a study focused on understanding how antimicrobial treatment disrupts gut-brain communication.

Join Zoom meeting at: https://unl.zoom.us/j/92732064797?pwd=RVJQVElTZ0VsdHE2NnVVREpUR0Nldz09

Meeting ID: 927 3206 4797
Passcode: 759697