Biological macromolecules or biological nanomachines play critical roles in all forms of life; for example, producing energies from the food we take and defending us from viruses. Knowledge of these nanomachines’ three-dimensional structures is essential for a deep understanding of how they perform complicated tasks in the cell. Dr. Limei Zhang, assistant professor of biochemistry and structural biology at the University of Nebraska–Lincoln, will discuss how to “see” these invisible biological nanomachines and how this information can be used to improve health and protect the environment.