Statistics and data science provide powerful methods, tools, and ways of thinking for solving problems and making decisions, but not everyone who could benefit from applying statistics and data science to their research has the knowledge or skills to apply it correctly. The Laboratory for Interdisciplinary Statistical Analysis (LISA) is a statistical collaboration laboratory that advances Virginia Tech’s land grant mission to generate, apply, and spread new knowledge throughout the state, the nation, and the world. LISA’s mission is to train statisticians to become interdisciplinary collaborators, provide research infrastructure to enable and accelerate high impact research, and engage with the community in outreach activities to improve statistical literacy. LISA has learned how to create statistical collaboration laboratories to train students to become effective statistical collaborators and to provide research infrastructure for the university.