Off-target movement of dicamba and 2,4-D, a concern with the introduction of dicamba-tolerant (DT) and 2,4-D-tolerant (Enlist) soybeans in North America and elsewhere. Therefore, field studies were being conducted in Nebraska to evaluate glyphosate-tolerant (GT) soybean response to micro-rates (0, 1/1000th, 1/500th, 1/100th, 1/50th, 1/10th) of the label rates of dicamba and 2,4-D applied at V2, V7/R1 and R2 soybean growth stages. Both herbicides negatively influenced multiple growth parameters of GT soybeans including visual injury, plant height, physiological maturity as well as yield and yield components. In all cases injuries and yield reductions from dicamba were significantly higher than those from 2,4-D for the same rate.