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Xinghui Sun, Ph.D. – CBC/RBC Seminar

LncRNA regulation of endothelial cell senescence in metabolic disease

Date: Time: 4:00 pm–5:00 pm
Beadle Center Room: E103 Auditorium
Additional Info: BEAD
Contact: Diana Bonham, (402) 472-2932,
The research program in Dr. Sun’s lab focuses on cellular senescence of vascular endothelium to identify new regulators such as long noncoding RNAs (lncRNAs) in metabolic disease. Cellular senescence is a fundamental mechanism underlying not only age-related decline in tissue function but also the pathogenesis of metabolic diseases. It has been shown that attenuation of cellular senescence ameliorates age-associated tissue dysfunction and the symptoms of metabolic diseases, including obesity, obese diabetes, atherosclerosis, and non-alcoholic steatohepatitis. A deeper understanding of the molecular mechanisms underlying endothelial cell senescence may lead to new therapeutic strategies for chronic metabolic disease.

Additional Public Info:
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Meeting ID: 932 2515 4270 Passcode: 563348

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This event originated in Biochemistry.