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Dr. Benjamin Orlando - CBC/RBC Seminar

Visualizing Dynamics of Membrane Transporters with Single-Particle Cryo-EM

Date: Time: 4:00 pm–5:00 pm
Directions: Zoom Link:
Meeting ID: 916 0286 1977
Contact: Diana Bonham, (402) 472-2932,
In recent years cryo-EM has emerged as the leading method to gain structural information on difficult membrane protein targets. Cryo-EM not only continues to produce near-atomic resolution structures of membrane proteins in near-native lipid bilayer environments, but has also developed into a method to characterize the conformational transitions that are critical to membrane protein function. Cryo-EM has proven particularly beneficial in analyzing the structural dynamics that allow membrane transporters to move solutes across biological membranes.

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This event originated in Biochemistry.