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Colloquium

Mathematics Colloquium

Date:
Time:
4:00 pm – 4:50 pm
Avery Hall Room: 115
1144 T St
 Lincoln NE 68508
Additional Info: AVH
Contact:
Steve Cohn, (402) 472-7223, scohn1@math.unl.edu
Speaker: Tomas Gedeon
Affiliation: Montana State University
Local Host: Wendy Hines
Title: How mathematical models can help biology:
Traffic flow model for bio-polymerization processes

Additional Public Info:
Abstract: Bio-polymerization processes like transcription and translation are central to a proper function of a cell. The speed at which the bio-polymer grows is affected both by number of pauses of elongation machinery, as well their numbers due to crowding effects. In order to quantify these effects in fast transcribing ribosome genes, we rigorously show that a classical traffic flow model is a limit of mean occupancy ODE model. We compare the simulation of this model to a stochastic model and evaluate the combined effect of the polymerase density and the existence of pauses on transcription rate of ribosomal genes.

Refreshments will be served in 348 Avery 3:30-4pm.
The talk is free and open to the public.

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