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NPOD seminar Peter Crawford (University of Minnesota)

“Protective interorgan and intercellular metabolite shuttles in obesity”

Date: Time: 12:00 pm–1:00 pm
via Zoom
Contact: Verona Skomski,
Peter Crawford is a Professor of Medicine and Director Division of Molecular Medicine at the University of Minnesota.
Obesity and cardiovascular disease are among the leading causes of morbidity and mortality worldwide. His research focuses on the interplay between intermediary metabolism and these disease processes. Derangements in the processing of carbohydrates, fats, and amino acids are central drivers of disease pathogenesis, but the roles of another metabolic fuel class, ketone bodies, are less well understood. They use novel genetic mouse models with engineered deficiencies in ketone body metabolism to study the metabolic shifts that occur in response to obesity, cardiovascular disease, and dynamic environmental challenges. From these models, they have developed new perspectives of how metabolism adapts in obesity, diabetes, nonalcoholic fatty liver disease (NAFLD/NASH), and cardiomyopathy; how these adaptations ultimately prove deleterious, and how innovative and personalized nutritional and pharmacological therapies may mitigate these adverse responses.
Join Zoom Meeting
Meeting ID: 925 5850 3804
Passcode: 362321

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